Dr Shruti Arora

Could Your Genes Increase Your Risk of Breast Cancer? Understanding BRCA1 and BRCA2

Breast cancer remains one of the most prevalent cancers worldwide, affecting approximately 2.3 million women annually, according to the World Health Organization (WHO) . While factors such as age, lifestyle, and environmental exposures can increase the risk of breast cancer, genetics plays a particularly important role in some cases.

What You Need to Know About Pancreatic Cancer: Key Symptoms, Risk Factors, and Treatment Options

Pancreatic cancer, often termed a silent killer due to its typically late diagnosis, is a growing concern in India. The National Cancer Registry Programme (NCRP) reports that pancreatic cancer contributes to a significant portion of cancer-related deaths, with a five-year survival rate of less than 10% in the country. The increasing incidence and low survival rates highlight the urgent need for awareness about its symptoms, risk factors, and available treatment options. Understanding these aspects can help in early detection and improve the chances of survival.

World Lymphoma Awareness Day

World Lymphoma Awareness Day, observed on September 15, serves as a crucial platform to increase awareness and understanding of lymphoma, a significant type of cancer affecting the lymphatic system. Lymphoma is not only one of the most common blood cancers but also a major health concern globally.

Blood Cancer Awareness Month: Understanding, Preventing, and Managing Blood Cancer

Blood Cancer Awareness Month

Blogs and Patient Guides Blood Cancer Awareness Month: Understanding, Preventing, and Managing Blood Cancer According to the GLOBOCAN 2020 report, India reported approximately 100,000 new cases of blood cancer in 2020 alone. Blood cancers account for around 7% of all cancer diagnoses in the country, making it one of the most common types of cancer. Unfortunately, the awareness level about blood cancer is relatively low, leading to delayed diagnoses and treatment. The 5-year survival rate for blood cancer patients in India is about 60%, though this varies widely depending on the type and stage of the cancer at diagnosis. Request An Appointment About Doctor Treatments Overview of Blood Cancer Types Blood Cancer Awareness Month Enlarge Image Blood cancers encompass a range of malignancies such as leukemia, lymphoma, myeloma, and other related disorders. Each type has its own distinct characteristics and treatment approaches, making awareness and education vital. Blood Cancer Awareness Month is an essential initiative to highlight the importance of raising awareness about blood cancers, including leukemia, lymphoma, and myeloma. These malignancies affect millions of people worldwide, and increasing public knowledge is crucial for early detection, effective treatment, and ultimately, saving lives. Importance of Blood Cancer Awareness, Early Detection, and Management Awareness is the first step towards early diagnosis, which significantly improves treatment outcomes. Understanding the signs, symptoms, and risk factors associated with blood cancer can lead to timely medical intervention and better prognosis. Understanding Blood Cancer: Symptoms, Causes, and Risk Factors What is Blood Cancer? Blood cancer, also known as hematologic cancer, refers to a group of cancers that affect the blood, bone marrow, and lymphatic system. These cancers disrupt the normal function of blood cells, impacting the body’s ability to fight infections and produce healthy blood cells. What are the Different Types of Blood Cancer? Leukemia: Originates in the bone marrow and leads to the production of abnormal white blood cells. Lymphoma: Begins in the lymphatic system and can spread to other parts of the body. Myeloma: Targets plasma cells in the blood, weakening the immune system. What Causes Blood Cancer? Blood cancer can be caused by a combination of genetic factors and environmental exposures, such as radiation or chemicals. These factors can lead to mutations in the DNA of blood cells, triggering the development of cancer. What are the Symptoms of Blood Cancer? Common symptoms of blood cancer include unexplained weight loss, persistent fatigue, frequent infections, easy bruising or bleeding, swollen lymph nodes, and bone pain. Specific symptoms may vary depending on the type of blood cancer. Who is at Risk for Blood Cancer? Risk factors for blood cancer include age, gender, family history, and exposure to certain chemicals or radiation. Understanding these risks can help in early detection and prevention strategies. How is Blood Cancer Diagnosed? Blood cancer is typically diagnosed through blood tests, bone marrow biopsies, and imaging studies. Early detection is key to improving prognosis and treatment outcomes. Preventing Blood Cancer: Tips and Strategies Can Blood Cancer Be Prevented? While genetic predispositions play a significant role, some lifestyle changes and preventive measures can reduce the risk of developing blood cancer. What Lifestyle Changes Can Reduce the Risk of Blood Cancer? Maintaining a healthy diet, exercising regularly, and avoiding smoking and harmful chemicals can lower the risk of blood cancer. How Does Regular Screening Help Prevent Blood Cancer? Regular health check-ups and screenings can detect blood cancer at an early stage, significantly improving treatment outcomes. What Role Does Family History Play in Blood Cancer? A family history of blood cancer increases the risk of developing the disease. Genetic counseling can help assess and manage this risk. Managing Blood Cancer: Treatment Options and Coping Strategies What Are the Treatment Options for Blood Cancer? Treatment options include chemotherapy, radiation therapy, stem cell transplantation, and targeted therapy. The choice of treatment depends on the type and stage of blood cancer. How Do Patients Cope with Blood Cancer? Managing blood cancer involves dealing with physical and emotional challenges. Support from family, friends, and healthcare professionals is crucial. What Are the Survival Rates for Blood Cancer? Survival rates vary depending on the type and stage of blood cancer. However, advances in treatment have improved survival rates significantly. What Lifestyle Changes Can Help Manage Blood Cancer? Adopting a healthy lifestyle, including proper nutrition, regular exercise, and stress management, can support the overall well-being of blood cancer patients. How Can Support Systems Help Blood Cancer Patients? Support systems, including family, friends, and healthcare teams, play a vital role in helping patients manage the challenges of blood cancer. Frequently Asked Questions About Blood Cancer What is the Difference Between Leukemia, Lymphoma, and Myeloma? Leukemia affects blood and bone marrow, lymphoma targets the lymphatic system, and myeloma involves plasma cells in the blood. Each type requires a different treatment approach. How Can I Get Involved in Blood Cancer Awareness Month? Participate in awareness campaigns, share information, and support blood cancer research and patients. What Should I Ask My Doctor if I’m Diagnosed with Blood Cancer? Important questions include understanding your specific type of blood cancer, treatment options, and what to expect during treatment. information, and support blood cancer research and patients. What Are the Latest Advances in Blood Cancer Research? Recent advancements include targeted therapies, immunotherapies, and improved diagnostic techniques, offering new hope for blood cancer patients. Conclusion Awareness, early detection, and proper management are crucial in the fight against blood cancer. Understanding the disease and supporting those affected can make a significant difference. How You Can Help During Blood Cancer Awareness Month Get involved by participating in awareness campaigns, donating to research organizations, and sharing information about blood cancer. Final Thoughts on the Importance of Blood Cancer Awareness and Early Detection Blood Cancer Awareness Month is an opportunity to spread knowledge, support those affected, and take proactive steps toward early detection and treatment. By raising awareness, we can save lives. Here is what you can do to raise awareness about blood cancer. If you or a loved one are experiencing symptoms of

How Does Immunotherapy Work to Treat Cancer?

Immunotherapy to Treat Cancer

Blogs and Patient Guides How Does Immunotherapy Work to Treat Cancer? Cancer is a disease that impacts millions of lives every year, with over 18 million new cases diagnosed globally in 2020 alone . Despite advances in traditional treatments like chemotherapy and radiation, these approaches often come with significant side effects and do not always offer long-term success. However, a new frontier in cancer treatment is emerging—immunotherapy. This innovative approach is not just a buzzword; it’s showing real promise, with studies. Another promising statistic: in certain types of cancers like melanoma, the five-year survival rate has improved dramatically with the introduction of immunotherapy, rising from 25% to over 50% . This growing field is changing the way we think about cancer treatment, offering new hope and possibilities for patients worldwide. Request An Appointment About Doctor Treatments What is Immunotherapy? Immunotherapy to Treat Cancer. Enlarge Image Immunotherapy is a type of cancer treatment that uses your body’s own immune system to fight cancer. Think of your immune system as your body’s natural defense force. It’s designed to protect you from harmful invaders like bacteria, viruses, and, yes, even cancer cells. But sometimes, cancer cells can sneak past your immune system without being detected. That’s where immunotherapy comes in—it helps your immune system recognize and destroy these hidden threats. How Immunotherapy Helps the Immune System Fight Cancer The immune system is a complex network of cells, tissues, and organs that work together to keep you healthy. Normally, it’s pretty good at spotting cells that aren’t behaving right, including cancer cells. However, cancer is tricky. It can hide from the immune system or even turn off the immune response that would normally destroy it. Cancer immunotherapy works by boosting your immune system’s ability to find and attack cancer cells. How Immunotherapy Works to Fight Cancer Enhancing Immune Recognition with Immunotherapy One of the key ways immunotherapy for cancer works is by helping the immune system recognize cancer cells that it might otherwise miss. By exposing hidden markers on these cells or blocking signals that suppress immune responses, immunotherapy makes the cancer visible to the body’s defenses. Boosting Immune Response with Immunotherapy Some types of immunotherapy treatment increase the overall activity of the immune system, making it stronger and more capable of attacking cancer cells. Targeting Specific Cancer Cells with Immunotherapy Many types of immunotherapy are designed to target cancer cells specifically, which means they leave healthy cells alone. This targeted approach reduces damage to normal tissues and leads to fewer side effects compared to traditional treatments like chemotherapy. Altering the Tumor Microenvironment with Immunotherapy The area around a tumor, known as the tumor microenvironment, can either help or hinder the growth of cancer. Some immunotherapies work by changing this environment to make it less supportive of cancer and more vulnerable to immune attacks. Benefits of Immunotherapy for Cancer Patients Long-lasting Protection from Cancer with Immunotherapy One of the most exciting benefits of cancer immunotherapy is its potential to offer long-lasting protection against cancer. Once your immune system is trained to recognize and fight cancer, it might continue to do so even after treatment ends, reducing the risk of the cancer coming back. Fewer Side Effects of Immunotherapy Compared to Chemotherapy Compared to chemotherapy, immunotherapy side effects are generally less severe. Since immunotherapy drugs are more targeted, they’re less likely to harm healthy cells, which means fewer and milder side effects. Immunotherapy’s Effectiveness Against Various Cancers Immunotherapy for cancer has shown success in treating a variety of cancers, including those that are difficult to treat with traditional methods, like melanoma, lung cancer, and certain types of lymphoma. Combining Immunotherapy with Other Treatments Immunotherapy can be combined with other treatments like chemotherapy and radiation to enhance its effectiveness. This combination can lead to better outcomes and a higher immunotherapy success rate. Side Effects of Immunotherapy Treatment and How to Overcome Them While immunotherapy has revolutionized cancer treatment, it’s important to be aware that, like any medical treatment, it can come with side effects. These side effects occur because immunotherapy drugs boost the immune system, which can sometimes cause it to attack not only cancer cells but also healthy cells. The intensity and type of side effects can vary depending on the specific immunotherapy treatment, the type of cancer, and the individual patient’s health. Common Side Effects of Immunotherapy Fatigue: Feeling tired or exhausted is one of the most common side effects of immunotherapy. This can range from mild to severe and can impact your daily activities. Skin Reactions: Rashes, itching, and dryness are common, especially with checkpoint inhibitors. These reactions usually appear where the immunotherapy drug is injected or in general areas like the face or limbs. Flu-like Symptoms: Fever, chills, muscle aches, and headaches can occur, mimicking symptoms of the flu. Digestive Issues: Diarrhea, nausea, and vomiting are frequent side effects that can lead to weight loss and dehydration if not managed properly. Autoimmune Reactions: Since immunotherapy enhances immune activity, it can sometimes cause the immune system to attack healthy organs, leading to conditions like colitis (inflammation of the colon), hepatitis (inflammation of the liver), or pneumonitis (inflammation of the lungs). Managing and Overcoming Immunotherapy Side Effects Communication with Your Healthcare Team: Always report any side effects to your oncologist immediately. Early intervention can prevent complications and manage symptoms more effectively. Rest and Energy Management: If fatigue is a significant issue, try to balance activities with periods of rest. Gentle exercise like walking can help boost energy levels, but listen to your body and don’t overdo it. Skincare Routine: For skin reactions, use mild, unscented moisturizers and avoid harsh soaps. Wearing loose-fitting, soft clothing can also help reduce irritation. Diet and Hydration: Stay hydrated and eat small, frequent meals to help manage digestive symptoms. Foods that are easy on the stomach, like bananas, rice, applesauce, and toast, can be helpful. Medications for Side Effects: Your doctor may prescribe medications to alleviate side effects like nausea or diarrhea. Over-the-counter antihistamines can also help with

Lung Cancer: An In-Depth Guide to Types, Risks, Symptoms, and Treatments.

World Lung Cancer Day

Blogs and Patient Guides Lung Cancer: An In-Depth Guide to Types, Risks, Symptoms, and Treatments . Lung cancer remains a major health challenge, being the leading cause of cancer death for both men and women worldwide. According to MedlinePlus, approximately 9 out of 10 cases of lung cancer in men and about 8 out of 10 cases in women are linked to tobacco smoking. Understanding lung cancer, from its types and symptoms to its treatments and preventive measures, is crucial in tackling this pervasive disease effectively. Request An Appointment About Doctor Treatments What is Lung Cancer? Lung Cancer. Enlarge Image Lung cancer is a type of cancer that starts in the lungs, usually in the cells that line the air passages. It’s a serious condition and, unfortunately, the leading cause of cancer-related deaths in both men and women. There are two main types of lung cancer, and understanding them can help you get a clearer picture of the disease. Types of Lung Cancer Small Cell Lung Cancer (SCLC) Small cell lung cancer is less common but tends to spread more quickly. It’s usually treated differently from other types of lung cancer due to its aggressive nature. Non-Small Cell Lung Cancer (NSCLC) Non-small cell lung cancer is the more common type and includes several subtypes like adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. These types grow and spread at different rates and respond differently to treatments. Who is at Risk for Lung Cancer? Lung cancer can affect anyone, but certain factors can increase your risk. Let’s break them down. 1. Smoking Smoking is the number one risk factor for lung cancer. It’s responsible for the majority of cases. The earlier you start, the longer you smoke, and the more cigarettes you smoke each day, the higher your risk. Even if you quit, the risk remains higher than in non-smokers, but it’s lower than if you continued smoking. 2. Secondhand Smoke Breathing in smoke from others’ cigarettes can also increase your risk. You’re exposed to the same harmful chemicals, just in smaller amounts. 4. Family History If lung cancer runs in your family, your risk is higher. Genetics can play a role in developing the disease. 5. Workplace Exposures Exposure to certain harmful substances at work can increase your risk of lung cancer. These substances include: Asbestos Arsenic Chromium Beryllium Nickel Soot Tar Radiation Exposure 6. Other Risk Factors: HIV Infection: People with HIV are at a higher risk. Air Pollution: Prolonged exposure to polluted air can contribute to lung cancer. What are the Symptoms of Lung Cancer? Sometimes, lung cancer doesn’t cause any noticeable symptoms, especially in the early stages. It might be found by accident during a chest X-ray for another condition. However, when symptoms do appear, they can include: Common Symptoms: Persistent Cough: A cough that doesn’t go away or worsens over time. Chest Pain: Discomfort in the chest area. Shortness of Breath: Trouble breathing. Wheezing: A wheezing sound when you breathe. Coughing up Blood: Blood in the mucus coughed up from the lungs. Hoarseness: Changes in your voice, making it sound raspy. Loss of Appetite: Not feeling hungry. Unexplained Weight Loss: Losing weight without trying. Fatigue: Feeling extremely tired. Difficulty Swallowing: Trouble swallowing food or liquids. Facial or Neck Swelling: Swelling in the face or neck veins. How is Lung Cancer Diagnosed? Diagnosing lung cancer involves several steps and tools. Here’s what to expect: 1. Medical and Family History: Your healthcare provider will ask about your symptoms and any family history of lung cancer. 2. Physical Exams:  A thorough physical exam can help identify any signs of lung cancer. 3. Imaging Tests: These tests create detailed pictures of the inside of your body like Chest X-ray, Chest CT Scan, etc.  4. Lab Tests: These tests can help detect cancer or other issues. Lab test like Blood tests,  Sputum tests, Lung Biopsies.  Staging If lung cancer is diagnosed, staging determines how far the cancer has spread. This information helps guide treatment decisions. What are the Treatments for Lung Cancer? Treating lung cancer depends on the type, stage, and your overall health. Here are the main treatment options: Treatment Options for Small Cell Lung Cancer (SCLC) : Surgery Chemotherapy Radiation Therapy Immunotherapy Laser Therapy Endoscopic Stent Placement: To open airways blocked by cancer. Treatment Options for Non-Small Cell Lung Cancer (NSCLC) Surgery Radiation Therapy Chemotherapy Targeted Therapy Immunotherapy Laser Therapy Photodynamic Therapy (PDT) Cryosurgery Electrocautery At work, follow safety guidelines to reduce exposure to harmful substances like asbestos and other carcinogens. Can Lung Cancer be Prevented? While not all lung cancers can be prevented, there are steps you can take to lower your risk: Avoid Smoking and Secondhand Smoke The most effective way to prevent lung cancer is to avoid smoking. If you don’t smoke, don’t start. Also, try to avoid being around smokers. Reduce Exposure to Hazardous Substances At work, follow safety guidelines to reduce exposure to harmful substances like asbestos and other carcinogens. Radon Testing Testing your home for radon can help you know if you need to take steps to reduce radon levels. Regular Screening Especially if you’re at high risk, regular screening can help detect lung cancer early when it’s more treatable. Resources and Further Information For more detailed information and resources, check out these organizations: Chronic HBV and HCV infections can increase the risk of bile duct cancer, although this is less common than liver cancer. The persistent inflammation and scarring in the bile ducts can lead to mutations and cancerous changes. National Cancer Institute They offer comprehensive resources on lung cancer, including types, treatments, and preventive measures. Centres for Disease Control and Prevention Offers support and resources for those living with lung cancer, including managing side effects, nutrition, and physical activity recommendations. Offers support and resources for those living with lung cancer, including managing side effects, nutrition, and physical activity recommendations. American Lung Association Offers support and resources for those living with lung cancer, including managing side effects, nutrition, and physical activity

Hepatitis B and C: Understanding the Link to Cancer.

Hepatitis is an inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems

Blogs and Patient Guides Hepatitis B and C: Understanding the Link to Cancer. Hepatitis B and C are serious health issues affecting millions of people worldwide. According to the World Health Organization (WHO), around 296 million people had chronic hepatitis B in 2019, and about 58 million had chronic hepatitis C in 2020. These infections not only harm the liver but also increase the risk of liver cancer and other serious conditions. This article explains what hepatitis is, the different types of hepatitis viruses, and how hepatitis B and C are linked to cancer. Understanding these viruses and taking preventive steps can help you protect your health and reduce the risk of serious complications. Request An Appointment About Doctor Treatments What is Hepatitis? Hepatitis is an inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems including cancer Enlarge Image Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. This swelling and damage can affect how well your liver functions. Hepatitis can be an acute (short-term) infection or a chronic (long-term) infection. Some types of hepatitis cause only acute infections. Other types can cause both acute and chronic infections of the liver, usually caused by a viral infection.  What Are the Different Types of Hepatitis Viruses? There are six types of hepatitis viruses: A, B, C, D, E, and G. Among these, hepatitis B and C are particularly concerning due to their strong association with cancer. What Exactly is Hepatitis B? Hepatitis B is a virus that targets the liver, leading to inflammation and potential long-term damage. It’s highly contagious and can be either acute (short-term) or chronic (long-term). What Are the Symptoms of Hepatitis B? Symptoms can vary from mild to severe and may include: Flu-like symptoms Jaundice (yellowing of the skin and eyes) Dark urine Abdominal pain Sometimes, especially in children, there may be no symptoms at all. How is Hepatitis B Diagnosed and Treated? Most Hepatitis B infections clear up on their own, hence follow-ups are recommended. In case of chronic infection, treatment is diagnosed through blood tests. Treatments include antiviral medications that help reduce the virus’s activity and prevent liver damage. In some cases, liver transplantation may be necessary for severe liver damage. What Exactly is Hepatitis C? Hepatitis C is a liver infection caused by the hepatitis C virus. It’s known for its tendency to remain asymptomatic in its early stages, often leading to chronic liver disease. What Are the Symptoms of Hepatitis C? Most people with hepatitis C don’t have symptoms at first. When symptoms do appear, they may include: Fatigue Jaundice Dark urine Abdominal pain How is Hepatitis C Diagnosed and Treated? Diagnosis involves blood tests to detect the presence of the virus. Modern antiviral medications can cure most cases of hepatitis C, significantly reducing the risk of severe liver disease. How do people get HBV and HCV? Hepatitis B and C spread through: Sexual contact with an infected person Sharing syringes or needles Contaminated medical or dental equipment Hepatitis B can spread through unprotected sex. Hepatitis C can also spread this way, but it’s less common. Both viruses can be passed from a mother to her baby during birth. Healthcare workers might be exposed if they accidentally get a needle stick or sharp injury from someone with hepatitis B or C. Hepatitis B and C are not spread by casual contact like hugging, shaking hands, sneezing, or coughing. They are not spread by air, food, or water. How Do Hepatitis B and C Increase Cancer Risk? Hepatitis B (HBV) and Hepatitis C (HCV) are viral infections that primarily affect the liver, leading to inflammation, fibrosis, and potentially severe liver damage. Both infections significantly increase the risk of developing liver cancer, specifically hepatocellular carcinoma (HCC). Understanding the mechanisms behind this increased risk is crucial for prevention and management. How Do Chronic Inflammation and Liver Damage Contribute? Both HBV and HCV cause chronic inflammation in the liver. Persistent inflammation leads to liver cell damage and attempts at repair, resulting in fibrosis and cirrhosis over time.   Cirrhosis, characterized by extensive scarring of the liver, significantly increases the risk of developing HCC. Up to 20% of individuals with chronic HCV and about 15-40% with chronic HBV may develop cirrhosis. How Does Viral Integration and Genetic Changes Play a Role? HBV can integrate its DNA into the host’s genome. This integration can disrupt normal cellular functions and promote genetic mutations, increasing the likelihood of cancerous cell transformations.   While HCV does not integrate into the host genome, it can still induce genetic mutations and chromosomal instability through indirect mechanisms like oxidative stress and chronic inflammation. How Do Immune Evasion and Immune System Suppression Increase Risk? Both viruses have strategies to evade the host immune system, allowing them to persist and cause prolonged liver damage.   Chronic HBV infection, for instance, can suppress immune responses, further facilitating liver damage and increasing cancer risk. What Factors Contribute to Worsening Liver Damage? Co-infection with other viruses such as HIV, lifestyle factors like alcohol abuse, and comorbid conditions such as obesity can worsen liver damage and increase the risk of developing Hepatocellular Carcinoma (HCC). Hepatocellular Carcinoma is a type of liver cancer that originates in the liver cells (hepatocytes). It often arises in the context of chronic liver disease, including cirrhosis caused by hepatitis infections or other liver conditions. Addressing these risk factors through preventive measures and effective management is crucial in reducing the likelihood of developing HCC. What Other Cancers Are Linked to Hepatitis B and C? Bile Duct Cancer (Cholangiocarcinoma): Chronic HBV and HCV infections can increase the risk of bile duct cancer, although this is less common than liver cancer. The persistent inflammation and scarring in the bile ducts can lead to mutations and cancerous changes. Non-Hodgkin Lymphoma: Studies have shown an association between HCV infection and an increased risk of non-Hodgkin